Inter-specific variation in entomopathogenic nematode foraging strategy : dichotomy or variation along a continuum ?

L'aptitude de six espèces de nématodes entomopathogènes ayant des comportements différents dans la recherche d'hôtes ayant eux-mêmes des taux de mobilité variables (#Galleria mellonella avec ou sans restriction de mouvement) a été évaluée. #Steinernema carpocapsae et #S. scapterisci ont tendance à se tenir droit sur leur queue sans se déplacer pendant des périodes de temps assez prolongées mais avec des mouvements de pendulation. Ces espèces utilisent une stratégie d'embuscade et sont les plus efficaces pour trouver les larves se déplaçant sans restriction de mouvement. #Heterorhabditis bacteriophora et #S. glaseri ne montrent pas de mouvement de pendulation et ont été les plus efficaces pour trouver les larves à déplacement restreint, ce qui est typique d'espèces cherchant leur hôte en se déplaçant. Une autre espèce sans mouvement de pendulation, #S. feltiae, et une espèce à pendulation peu fréquente, #S. riobravis, peuvent atteindre les deux types d'hôtes, ce qui suggère qu'elles ont un comportement intermédiaire de recherche d'hôtes. La stratégie intermédiaire de #S. feltiae pourrait être due à sa capacité à élever de plus de 30% son corps au-dessus du support (mouvement de pendulation), et ce, plus fréquemment que les autres espèces sans mouvement pendulaire. (Résumé d'auteur

Estimation of entomopathogenic nematode population density in soil by correlation between bait insect mortality and nematode penetration

Il est décrit une méthode d'estimation des larves infestantes de nématodes entomopathogènes présentes dans des échantillons de sol, méthode basée sur des échantillonnages répétés des larves de #Galleria mellonella$ jouant le rôle d'appât. L'efficacité d'extraction de cette méthode est très élevée et elle apparaît beaucoup plus rapide que les autres méthodes en usage. Dix larves sont placées dans chaque échantillon et sont régulièrement remplacées par de nouveaux insectes jusqu'à ce que l'infestation par les nématodes cesse. L'estimation de la densité des nématodes est basée sur une relation linéaire forte entre le log10 du nombre de larves infestées par les nématodes et le log10 du nombre de nématodes retrouvés dans ces larves. Cette relation a été calculée pour deux espèces de nématodes dans des échantillons provenant du champ (populations naturelles) et en laboratoire pour trois espèces de nématodes et trois types de sol. La pente de la courbe de régression linéaire ne présente qu'une faible variation entre essais, espèces et types de sol. (Résumé d'auteur

Generating expressive speech for storytelling applications

Work on expressive speech synthesis has long focused on the expression of basic emotions. In recent years, however, interest in other expressive styles has been increasing. The research presented in this paper aims at the generation of a storytelling speaking style, which is suitable for storytelling applications and more in general, for applications aimed at children. Based on an analysis of human storytellers' speech, we designed and implemented a set of prosodic rules for converting "neutral" speech, as produced by a text-to-speech system, into storytelling speech. An evaluation of our storytelling speech generation system showed encouraging results

Defining and investigating difficult asthma: Developing quality indicators

SummaryBackgroundThere is no agreed definition of ‘difficult asthma’ or what investigations should be available to investigate these patients. Patients with difficult asthma remain symptomatic on high levels of treatment and are high users of medical resources.AimTo develop a set of quality indicators for the definition and investigation of difficult asthma.MethodModified RAND Appropriateness Method was used. An expert panel composed of nine hospital asthma specialists who run ‘difficult’ asthma clinics and were identified from a shortlist of key workers in the field. Indicators were rated as necessary to define and investigate difficult asthma.ResultsDifficult asthma was defined as ‘symptoms persisting beyond therapy consistent with step 4 of the British Thoracic Society (BTS) guidelines’ (high dose inhaled corticosteroids and long acting β2-agonists). Eighty-three indicators were identified (40 relating to definition and 43 relating to investigations). Of these 32 (39%) were rated as necessary: 7 out of 40 (18%) for defining difficult asthma and 23 out of 43 (53%) for investigations. Indicators of high medical resource usage were characteristic of the ‘difficult’ nature of the management of patient with difficult asthma. A framework for the investigation of these patients was created.ConclusionThe listed performance indicators identify a range of requirements that are necessary to define difficult asthma. Targeting of real needs in this group of patients will lead to better patient care and reduction of ‘waste’ in provision of healthcare

Gluino Pair Production at Linear e^+e^- Colliders

We study the potential of high-energy linear $e^+e^-$ colliders for the production of gluino pairs within the Minimal Supersymmetric Standard Model (MSSM). In this model, the process $e^+e^-\to\tilde{g}\tilde{g}$ is mediated by quark/squark loops, dominantly of the third generation, where the mixing of left- and right-handed states can become large. Taking into account realistic beam polarization effects, photon and $Z^0$-boson exchange, and current mass exclusion limits, we scan the MSSM parameter space for various $e^+e^-$ center-of-mass energies to determine the regions, where gluino production should be visible.Comment: 22 pages, 9 figure

SUSY-QCD Effect on Top-Charm Associated Production at Linear Collider

We evaluate the contribution of SUSY-QCD to top-charm associated production at next generation linear colliders. Our results show that the production cross section of the process $e^+e^-\to t\bar c{or}\bar t c$ could be as large as 0.1 fb, which is larger than the prediction of the SM by a factor of $10^8$.Comment: version to appear in PR

Towards a New Standard Model for Black Hole Accretion

We briefly review recent developments in black hole accretion disk theory, emphasizing the vital role played by magnetohydrodynamic (MHD) stresses in transporting angular momentum. The apparent universality of accretion-related outflow phenomena is a strong indicator that large-scale MHD torques facilitate vertical transport of angular momentum. This leads to an enhanced overall rate of angular momentum transport and allows accretion of matter to proceed at an interesting rate. Furthermore, we argue that when vertical transport is important, the radial structure of the accretion disk is modified at small radii and this affects the disk emission spectrum. We present a simple model demonstrating how energetic, magnetically-driven outflows modify the emergent disk emission spectrum with respect to that predicted by standard accretion disk theory. A comparison of the predicted spectra against observations of quasar spectral energy distributions suggests that mass accretion rates inferred using the standard disk model may severely underestimate their true values.Comment: To appear in the Fifth Stromlo Symposium Proceedings special issue of ApS

The Symptoms of Varicose Veins: Difficult to Determine and Difficult to Study

ObjectivesTo investigate the activities which may exacerbate symptoms in patients with varicose veins.MethodsQuestionnaires sent to patients before clinics and at least six months later.ResultsBoth questionnaires were returned by 149 of 203 patients (74%) but only 124 contained adequate data for comparison – 55 from patients who had surgical treatment and 69 who had no surgery. At initial presentation, worsening of discomfort attributed to varicose veins was common during (58%) or after (48%) standing and in hot weather (44%), but less when sitting with the feet down (31%), and after (31%) or when walking (19%). Surgery significantly reduced the total number of symptoms reported by patients at follow-up (p<0.02). However, none of the symptoms reported during specific activities was significantly lessened by surgery compared with no treatment – possibly because the attrition of patients during the study resulted in small numbers for analysis.ConclusionsSymptoms are a common indication for treating varicose veins and it is therefore important to be sure that they are due to the veins, rather than other causes. This report highlights traditional and logical questions which may help to identify symptoms caused by varicose veins but illustrates the difficulty of validating them

Spatial Analysis of Single Allocation Hub Location Problems

Hubs are special facilities that serve as switching, transshipment and sorting nodes in many-to-many distribution systems. Flow is consolidated at hubs to exploit economies of scale and to reduce transportation costs between hubs. In this article, we first identify general features of optimal hub locations for single allocation hub location problems based on only the fundamental problem data (demand for travel and spatial locations). We then exploit this knowledge to develop a straightforward heuristic methodology based on spatial proximity of nodes, dispersion and measures of node importance to delineate subsets of nodes likely to contain optimal hubs. We then develop constraints for these subsets for use in mathematical programming formulations to solve hub location problems. Our methodology can also help narrow an organization’s focus to concentrate on more detailed and qualitative analyses of promising potential hub locations. Results document the value of including both demand magnitude and centrality in measuring node importance and the relevant tradeoffs in solution quality and time. © 2015, Springer Science+Business Media New York